In a pivotal move to tackle America’s overdose epidemic, the U.S. Department of Health and Human Services (HHS) has announced $25.6 million in federal funding to expand medication-assisted treatment for opioid use disorder and bolster prescription drug misuse prevention. Rolled out through the Substance Abuse and Mental Health Services Administration (SAMHSA), this funding underscores the Biden administration’s ongoing commitment to improving mental health and behavioral health outcomes across the country.
As overdose deaths—largely driven by synthetic opioids—continue to soar, this initiative delivers much-needed support to states, tribes, and local agencies working on the frontlines of the crisis.
The Programs: Treatment Expansion and Targeted Prevention
The HHS funding will be divided between two major grant programs with complementary goals:
1. Medication-Assisted Treatment – Prescription Drug and Opioid Addiction (MAT-PDOA)
- Funding Total: $22.6 million over five years
- Purpose: To enhance access to medication-assisted treatment for opioid use disorder, focusing on underserved populations and high-need regions.
- Equity Commitment: At least $11 million is earmarked specifically for Native American tribes, tribal organizations, or consortia, ensuring culturally appropriate and accessible treatment.
2. Strategic Prevention Framework for Prescription Drugs (SPF-Rx)
- Funding Total: $3 million over five years
- Purpose: To support state and tribal efforts to prevent prescription drug misuse, particularly in communities with existing strategic prevention frameworks.
Together, these programs are designed to close treatment gaps and reduce the misuse of opioids and other prescription medications at scale.
A Nation in Crisis: Why Action Is Urgent
According to the Centers for Disease Control and Prevention (CDC), over 99,000 overdose deaths occurred in the 12 months ending in September 2021, with projections pointing to more than 104,000 deaths once the final numbers are in. The vast majority are attributed to synthetic opioids such as fentanyl, which is now a leading cause of death for Americans aged 18–45.
Public health officials estimate that 1.2 million opioid-related deaths occurred across North America by the end of 2019.
“Every five minutes someone in our nation dies from an overdose,” said HHS Secretary Xavier Becerra. “This is unacceptable. We are committed to addressing the overdose crisis by expanding access to medication-assisted treatment for opioid use disorder and other effective, evidence-based strategies.”
Why Medication-Assisted Treatment for Opioid Use Disorder Works
Medication-assisted treatment for opioid use disorder is a comprehensive, evidence-based approach that combines FDA-approved medications (like buprenorphine, methadone, and naltrexone) with counseling and behavioral therapies. Research shows that MAT:
- Reduces opioid cravings and withdrawal symptoms
- Lowers the risk of fatal overdose by more than 50%
- Increases retention in treatment programs
- Reduces criminal activity and improves employment outcomes
- Supports better prenatal outcomes for pregnant individuals
Despite its effectiveness, medication-assisted treatment for opioid use disorder remains underutilized in many parts of the country due to stigma, workforce shortages, and lack of access—especially in rural and tribal communities.
Focus on Equity: Addressing Racial and Geographic Disparities
The opioid epidemic has evolved from its origins in predominantly white, rural areas. Today, Black, Hispanic, Native American, and Alaska Native populations are experiencing rapidly increasing overdose rates.
A recent JAMA Psychiatry study found that overdose death rates among Black individuals have surpassed those of white individuals in several major cities. Native and Indigenous populations also face disproportionately high overdose mortality rates.
The federal grant prioritizes outreach and funding for tribal communities, with nearly half of MAT-PDOA funds directed toward Native American health services. By supporting medication-assisted treatment for opioid use disorder in these historically underserved areas, HHS aims to reverse disparities and improve health equity.
Supporting Statewide Prevention Efforts
While MAT focuses on treatment, the SPF-Rx program provides resources for prevention. States and tribal governments with existing Strategic Prevention Frameworks will receive funding to:
- Educate communities about the risks of prescription drug misuse
- Promote safe medication storage and disposal
- Improve prescribing practices
- Coordinate with schools, healthcare providers, and community coalitions
This dual approach—treating current OUD and preventing future misuse—ensures a more sustainable, long-term impact.
Leadership Commitment to Long-Term Recovery
Dr. Miriam Delphin-Rittmon, Assistant Secretary for Mental Health and Substance Use and head of SAMHSA, stressed the importance of access and sustainability:
“Expanding access to evidence-based treatments and supports for individuals struggling with opioid use disorder has never been more critical. Strengthening the nation’s prescribing guidelines to prevent misuse is equally critical.”
The Biden administration has made medication-assisted treatment for opioid use disorder a cornerstone of its broader behavioral health strategy. This includes expanded access to naloxone, increased telehealth capacity, and support for harm reduction programs.
Building a Better Future, One Community at a Time
With $25.6 million in targeted federal support, SAMHSA and HHS are equipping communities with the tools they need to save lives. Whether through improving prescribing education, reducing stigma, or expanding medication-assisted treatment for opioid use disorder, this funding is a critical step toward addressing one of the most pressing public health challenges of our time.
But more work remains. To fully curb the epidemic, we need ongoing investment in:
- Peer support and recovery coaching
- Culturally responsive care models
- Affordable, long-term recovery housing
- Mental health integration with primary care
- Community-level data collection and monitoring
Conclusion: Hope Through Access and Evidence-Based Care
The overdose crisis has claimed hundreds of thousands of lives. Yet, solutions exist—and with adequate funding and the right strategy, recovery is possible.
This new round of SAMHSA grants demonstrates a renewed federal commitment to medication-assisted treatment for opioid use disorder, prevention education, and equitable care for all communities.
As Secretary Becerra noted, the loss of life is unacceptable—but with bold leadership and evidence-based policy, change is not only possible, it is already underway.
Need Help?
If you or someone you know is struggling with opioid use, call the SAMHSA National Helpline at 1-800-662-HELP (4357). Support is free, confidential, and available 24/7.
